@article{MAKHILLJAVA20121193386,
    title = {Pancreatic Abnormalities at a Young Age in Spontaneously Diabetic Torii (SDT) Rats},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {9},
    pages = {1322-1326},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.1322.1326},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.1322.1326},
    author = {Takahisa Yamada,Takeshi,Masami and},
    keywords = {HOMA,IGT,SDT rat,reduction,insulin content,pancreatic},
    abstract = {The Spontaneously Diabetic Torii (SDT) rat is a non-obese diabetic model showing various metabolic abnormalities in pre-diabetic stage. In this study, researchers investigated the pancreatic function at young ages, 5 and 7 weeks. At 5 weeks, SDT rats showed glucose intolerance and reduction of Homeostasis Model Assessment (HOMA)-β. At 7 weeks, the insulin content in pancreas was also decreased. Insulinogenic index showed no change at 5 and 7 weeks of age. In conclusion, the pancreatic function in SDT rats was decreased from a young age after weaning and the rat is a useful Animal Model to examine the pathophysiological features of Impaired Glucose Tolerance (IGT).}
    }