@article{MAKHILLJAVA20121173338,
    title = {Influence of Selenium on Hepatic Antioxidant Capacity in Ducklings Intoxicated with Afatoxin B<SUB>1</SUB>},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {11},
    number = {7},
    pages = {1052-1055},
    year = {2012},
    issn = {1680-5593},
    doi = {javaa.2012.1052.1055},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2012.1052.1055},
    author = {S.N.,D.Y.,S.Q.,R.S.,R.Q.,Y.C. and},
    keywords = {Selenium,hepatic antioxidant capacity,afatoxin B1,activity,ducklings,dysfunction},
    abstract = {To investigate the influence of selenium on hepatic antioxidant capacity in ducklings administrated with Afatoxin B<SUB>1</SUB> (AFB<SUB>1</SUB>), ninety 7 days old ducklings were randomly divided into three groups (groups I-III). Group I was used as a blank control. Group II was administered with AFB<SUB>1</SUB> (0.1 mg kg<SUP>-1</SUP> body weight). Group III was administered with AFB<SUB>1</SUB> (0.1 mg kg<SUP>-1</SUP> body weight) plus selenium (sodium selenite, 1 mg kg<SUP>-1</SUP> body weight). All treatments were given once daily for 21 days. The results showed that the activity of hepatic Superoxide Dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GSH-Px) and Glutathione Reductase (GR) in group II ducklings significantly decreased when compared with group I (p&lt;0.01). Furthermore, the content of hepatic Malondialdehyde (MDA) significantly increased (p&lt;0.01). However, the activities of hepatic SOD, CAT, GSH-Px and GR in group III ducklings significantly increased when compared with group II (p&lt;0.05). In addition, the content of hepatic MDA significantly decreased (p&lt;0.01). These results revealed that AFB<SUB>1</SUB> significantly induced hepatic antioxidant function dysfunction. However, selenium could significantly alleviat the negative effect induced by AFB<SUB>1</SUB>.}
    }