@article{MAKHILLJAVA20111042613,
    title = {Expression of Augmenter of Liver Regeneration and Nuclear Faction-κB in Human Hepatocellular Carcinoma},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {4},
    pages = {480-483},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.480.483},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.480.483},
    author = {Zhang and},
    keywords = {Augmenter of liver regeneration,China,partial role,clinicopathological,hepatocellular carcinoma,nuclear faction-ºB},
    abstract = {To determine whether the levels of expression of the Augmenter of Liver Regeneration (ALR) and nuclear faction-κB(NF-κB) were assoiated with the clinicopathological features in human Hepatocellular Carcinoma (HCC). Gene expression was measured by using RT-PCR in the 30 human HCC tissues, matched adjacent tissues and 8 normal hepatic tissues. The clinicopathological data of all patients were also collected. Higher expression of ALR mRNA was observed in HCC tissues compared with normal liver tissue (p<0.05), it did not differ from the expression of matching non-neoplastic tissue in the same patient (p>0.05). Expression of both two genes were not found to be significantly associated with clinical/pathologic factors. (p>0.05). The expression of ALR mRNA in HCC tissues was positively correlated with NF-κB mRNA (r = 0.382, p<0.05). Up-regulation of ALR may play partial role of carcinogenesis through MAPK pathway in HCC.}
    }