@article{MAKHILLJAVA20111032587,
    title = {The Effect of an Attenuated Rabies Virus SRV<SUB>9</SUB> on Suckling Mouse Growth After Intracerebral Inoculation},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {3},
    pages = {322-326},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.322.326},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.322.326},
    author = {Rongliang,Ziguo,Zhuang,Shoufeng,Chenglong,Yuzhu and},
    keywords = {suckling mouse,vaccination,Rabies Virus (RV),intracerebrally inoculation,growth,SRV9 strain},
    abstract = {Rabies virus is a kind of virus having strict neurotropic property. Intracerebral inoculation method was commonly used to RV-related research. SRV<SUB>9</SUB> is an attenuated RV vaccine strain. In the present study, we inoculated intracerebrally on suckling mouse with SRV<SUB>9</SUB> strain. The results showed that SRV<SUB>9</SUB> could cause a mortality rate of 100% on suckling mice below 13 day old. The mortality rates of 14-17 day old mice were 68, 33, 33 and 17%, respectively without incidence above 18 day old. Meanwhile, the results showed that the growth of survival suckling mice was inhibited remarkably after intracerebral inoculation SRV<SUB>9</SUB>. The 16 day old survival suckling mice were chosen to perform body weight test and the result showed that the weight growth was very slow with 14% less than normal growth rate. However, 2 weeks latter the weight of the mice began to recover gradually but slowly. It was suggested that the intracerebral RV reproduction could take a significant effect on the growth and development of the mice and with RV being eliminated by antibody, the weight of the mice which were inoculated with SRV<SUB>9</SUB> could gradually recover.}
    }