@article{MAKHILLJAVA201110182963,
    title = {Effect of Rumen Degradable Protein Supplementation on Purine Derivatives Excreted Through Urine and Milk in Lactating Holstein Cows},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {18},
    pages = {2389-2393},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.2389.2393},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.2389.2393},
    author = {Mehdi,Kamran,Hossein Ali,Amir Hossein,Mehdi and},
    keywords = {milk,lactating cows,urine spot sampling,Purine derivatives,urine,uric acid},
    abstract = {This study was conducted to evaluate the effect of Supplemented 
  Rumen Degradable Protein (SRDP) on excretion of Total Purine Derivatives (TPD; 
  urinary allantoin, urinary uric acid, milk allantoin and milk uric acid) and 
  contribution of purine derivatives excreted through urine or milk in TPD. Multiparous 
  lactating Holstein cows (n = 15) with an average Body Weight (BW) of 643 kg, 
  days in milk; 21 days and milk yield 30 kg days&#8226;<SUP>1</SUP> fed a basal 
  diet with different levels of SRDP (treatments 1-3 were 0, 50 and 100 g days&#8226;<SUP>1</SUP> 
  SRDP, respectively). The TPD excretion was 464.81, 468.70 and 480.83 mmol days&#8226;<SUP>1</SUP> 
  for treatments 1-3, respectively (p = 0.009). Urinary allantoin (p = 0.01) and 
  uric acid (p = 0.04) and milk allantoin (p = 0.02) were affected but milk uric 
  acid was not affected by SRDP. Although, the amounts of excreted purines affected 
  with SRDP, the contribution of Urinary Purine Derivatives (UPD) and Milk Purine 
  Derivatives (MPD) to TPD were approximately constant. Urinary allantoin, urinary 
  uric acid, milk allantoin and milk uric acid accounted approximately 91.63, 
  4.54, 3.07 and 0.73% of excreted TPD, respectively. In conclusion, regardless 
  the effect of SRDP, the results indicate that urinary allantoin accounted the 
  greatest and milk uric acid accounted the least contribution in TPD excretion 
  in lactating Holstein cows.}
    }