@article{MAKHILLJAVA201110112797,
    title = {The Association of ANKRD2 with Loin Depth and Muscle Firmness in Pigs},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {10},
    number = {11},
    pages = {1462-1468},
    year = {2011},
    issn = {1680-5593},
    doi = {javaa.2011.1462.1468},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2011.1462.1468},
    author = {Bang,Ling,Xinjie and},
    keywords = {ANKRD2,meat quality trait,expression profile,association analysis,Sequence analysis,carcass trait},
    abstract = {The Muscle Ankyrin Repeat Proteins (MARPs) family is essential for cardiogenesis and Cardiac hypertrophy (CARP), skeletal muscular stretch and development (ANKRD2/ARPP) and during recovery following starvation (DARP). Here we describe the isolation and molecular characterization of the full-length cDNA of porcine gene <I>ANKRD2 </I>(ankyrin repeated domain 2). The cDNA sequence and predicted protein sequence shared high sequence identity with other mammalian counterparts. The Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) revealed that ANKRD2 has a high level of expression in skeletal muscle and a low expression in heart while the other tissues being tested had no expression. The expression of <I>ANKRD2</I> gene was up-regulated accompanying with the different embryo developmental stages (embryo 33, 65, 90 days; postnatal 2 days, adult) and reached the peak at the adult time. A T/C single nucleotide polymorphism in ANKRD2 exon5 was detected and a HaeIII PCR-Restriction Fragment Length Polymorphism (PCR-RFLP) was then developed. Association of the genotypes with growth and carcass traits revealed significant associations of the porcine ANKRD2 loin depth (p&lt;0.05) and firmness (p&lt;0.05).}
    }