@article{MAKHILLJAVA20109202441,
    title = {Effects of Vitamin E, Vitamin C and Mannanoligosaccharide (Bio-Mos<SUP>&reg;</SUP>) Supplements on Performance and Immune System in Broiler Chicks},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {9},
    number = {20},
    pages = {2647-2654},
    year = {2010},
    issn = {1680-5593},
    doi = {javaa.2010.2647.2654},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2010.2647.2654},
    author = {H.,M.,F.,C. and},
    keywords = {Broiler chick,immune system,vitamin E,vitamin C,mannanoligosaccharide,performance},
    abstract = {Maintaining gut health is important for the production of high quality and profitable poultry. The goal of this study was to examine the effects of supplemental mannan oligosaccharide (Bio-MOS<SUP>&reg;</SUP>), Vitamin E (VE) and C (VC) on the growth performance and immune response of broilers given a corn based diet over a 6 weeks experimental period. About 1 day old male broilers (n = 300) were randomly distributed to 4 groups (75 birds in each group and 15 birds in each subgroup for repetation 5 times) and reared under similar conditions. Standard husbandry and good management practices were followed that met or exceeded industry guideline. At each feeding, the following treatments were administered: control (no Bio-MOS<SUP>&reg;</SUP>, VE and VC), 1.5 g kg<SUP>-1</SUP> Bio-MOS<SUP>&reg;</SUP>, 500 &#956;g kg<SUP>-1</SUP> VE and 500 &#956;g kg<SUP>-1</SUP> VC. Body Weights (BW), Feed Intake (FI) and Feed Conversion Ratio (FCR) were measured on day 1, 21 and 42. Blood samples were taken from vena ulnaris every 7 days and were analyzed on IgG concentration. The results showed that there was no significant difference in BW, FI and FCR among the treatment groups. During the 6 weeks of trial period considering plasma IgG levels significant differences were only found as following: compared to control group it was significantly lower in VE group at week 1 and 2, higher in VC and Bio-MOS<SUP>&reg;</SUP> groups at week 2 and lower in Bio-MOS<SUP>&reg;</SUP> group at week 6. Additionally, at 4 week lowest (0.90&plusmn;0.06 mg, n = 15) and at 5 week highest (2.85&plusmn;0.18 mg, n = 15) plasma IgG level was found after applying the dietary treatment in Bio-Mos<SUP>&reg;</SUP> group. Consequently, this data suggest that supplementation of Bio-MOS<SUP>&reg;</SUP>, VE or VC may not improve either broiler performance or immune response in healthy broilers.}
    }