@article{MAKHILLJAVA20109182400,
    title = {Nephrocalcinosis and Urinary Mineral Concentrations in Rats Fed Diets Containing Various Concentrations of Magnesium},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {9},
    number = {18},
    pages = {2405-2408},
    year = {2010},
    issn = {1680-5593},
    doi = {javaa.2010.2405.2408},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2010.2405.2408},
    author = {H.E.,A. and},
    keywords = {Rats,nephrocalcinosis,diet,urine,magnesium,phosphorus,concentrations},
    abstract = {High magnesium intakes are known to inhibit the development of nephrocalcinosis in female rats but there was no information on the dose-response relationship and the underlying mechanism. In an attempt to collect the lacking information, female rats were fed diets containing 0.02-0.24% magnesium as the only variable. Increasing dietary magnesium concentrations were found to reduce nephrocalcinosis in a dose-dependent fashion. The lowest dietary magnesium level produced a kidney calcium concentration of 10.6% in the dry matter whereas the highest magnesium intake reduced kidney calcium to 0.2%. Increasing dietary magnesium concentrations produced increasing urinary magnesium concentrations in combination with decreasing phosphorus concentrations. It is suggested that the magnesium-induced inhibition of nephrocalcinosis is caused by a decrease in urinary phosphorus and increase in urinary magnesium.}
    }