@article{MAKHILLJAVA20109182390,
    title = {Molecular Characteristics of the Porcine <I>MUSTN1</I> Gene and its Significant Association with Economic Traits},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {9},
    number = {18},
    pages = {2351-2356},
    year = {2010},
    issn = {1680-5593},
    doi = {javaa.2010.2351.2356},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2010.2351.2356},
    author = {B.,X.W. and},
    keywords = {association analysis,SNP,MUSTN1,Pig,meat quality traits,expression},
    abstract = {The <I>MUSTN1</I> (musculoskeletal, embryonic nuclear protein 1) gene plays an important role in the development and regeneration of the mammalian musculoskeletal system and has a high expression in the muscle. In the present study, we cloned the porcine <I>MUSTN1</I> genome DNA sequence including the full-length cDNA. Analysis of the genomic sequence revealed that porcine <I>MUSTN1</I> consists of 3 exons separated by 2 introns. It contains a 237 bp open reading frame flanked by 251 bp 5&#146;UTR and 216 bp 3&#146;UTR. Radiation hybrid mapping data indicated that the porcine <I>MUSTN1</I> gene was located to chromosome 13q12-q22. The expression data revealed that the porcine <I>MUSTN1</I> gene is widely expressed in the examined tissues and has an especially high expression level in muscle tissues. One single nucleotide polymorphism c. 265C &gt;T was identified in the 3&#146;UTR of the porcine <I>MUSTN1</I> gene and genotyped by the NruI PCR-RFLP. Association analysis showed that different genotypes of the <I>MUSTN1</I> gene were significantly associated with ADG (average daily gain from birth to 100 kg), percentage of ham, proportion of lean and bone of the ham and meat color (p&lt;0.05). Thus, the mutation can be applied to pig breeding by molecular Marker-Assisted Selection (MAS).}
    }