@article{MAKHILLJAVA200875768,
    title = {Cytokine Immune Response in Mexican Creole and Commercial Pigs Under Uncontrolled Conditions},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {7},
    number = {5},
    pages = {625-629},
    year = {2008},
    issn = {1680-5593},
    doi = {javaa.2008.625.629},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2008.625.629},
    author = {K. Mejia-Martinez,C. Lemus-Flores,J.F. Zambrano-Zaragoza,R. Ramirez-Necoechea,D. Mota-Rojas and},
    keywords = {Cytokines,humoral immune response,creole pigs},
    abstract = {The aim of the study was to measure the cytokine immune response in 2 Mexican creole biotypes and compare it to commercial pigs (COM) as disease resistance indicators. Twenty six commercial (COM), 25 Cuino (CP) and 25 Mexican hairless (MHP) pigs were vaccinated with a commercial bacterin containing <I>Salmonella</I>, <I>E. coli</I> and <I>Pasteurella</I> at 45 days of age; a sample was taken a week later to test serum levels of interleukin 1  (IL-1 ), interleukin 4 (IL-4), interferon-gamma (INF- ) and alfa tumor necrosis factor (TNF- ). Cytokine quantification serum tests were carried out with commercial kits using the ELISA sandwich method. The Kruskal-Wallis test was used to compare cytokine concentrations and the Wilcoxon test was run to look for differences among breeds. IL-1  and IL-4 production was higher in HMS as compared to the other breeds. No significant differences between INF-  and TNF-  production were seen. Results suggest that MHP have a higher response capacity before an infection, compared to the other breeds.}
    }