@article{MAKHILLJAVA20065171,
    title = {Relationships Between Plasma Cortisol, Corticosteroid-binding Globulin 
(CBG) and The Free Cortisol Index (FCI) In Pigs Over A 24 h Period},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {5},
    number = {1},
    pages = {85-91},
    year = {2006},
    issn = {1680-5593},
    doi = {javaa.2006.85.91},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2006.85.91},
    author = {Rebecca J. Adcock,Henry G. Kattesh,Mary P. Roberts,Arnold M. Saxton and},
    keywords = {Pig,cortisol,Corticosteroid-Binding Globulin (CBG),Free Cortisol Index (FCI)},
    abstract = {The relationship between plasma free cortisol and the free cortisol index (FCI, the ratio of cortisol to CBG) was evaluated in eight 8-wk old pigs over a 24 h period and in response to administration of saline or ACTH. A high (p<0.001) correlation was found between actual free cortisol and the FCI in both saline (r = 0.73) and ACTH (r = 0.85) treated pigs. A diurnal rhythm was apparent for total cortisol, free cortisol, percent free cortisol, pCBG and the FCI. Total cortisol (p<0.05), free cortisol (p<0.05) and the FCI (p<0.01) were elevated during the first four h following administration of ACTH. Concentrations of pCBG differed (p<0.001) over time and were higher (p<0.01) for ACTH treated pigs over the 24 h period. The results from this study affirm the contention that FCI is a suitable estimate of free cortisol in swine.}
    }