@article{MAKHILLJAVA2005481114,
    title = {Oral Administration of Lasalocid Causes Peripheral Neuropathy in Sprague Dawley Rats:Effect of Water Salinity on Lasalocid-induced Peripheral Neuropathy},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {4},
    number = {8},
    pages = {719-722},
    year = {2005},
    issn = {1680-5593},
    doi = {javaa.2005.719.722},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2005.719.722},
    author = {Asim Kart,Stanley Leon Vanhooser and},
    keywords = {Lasalocid,ataxia,neurotoxicity,heat stress,salinity},
    abstract = {Lasalocid toxicity was associated with several neurotoxicity cases in animal species. Incidence of lasalocid neurotoxiciy shows a higher rate in chickens during heat stress with increased water salinity. In the present study, It studied the effect of lasalocid with or without 0.9 % NaCl in male Sprague Dawley. The rats were given 0, 10, 20, 40 mgkgG of lasalocid two times a day for 3 days with or without 0.9 % saline in the 1 drinking water. Rats showed ataxia in the 20 and 40 mgkgG dose groups with higher death rate in group 1 receiving 40 mgkgG of lasalocid. Dietary salt did not affect ataxia induced by lasalocid. While the optimum dose 1 to produce ataxia (without high mortality) appears to be 20 mgkgG of lasalocid, increasing salinity of water has 1 no effect on the neurotoxicity of lasalocid.}
    }