@article{MAKHILLJAVA200324505,
    title = {Effect of Dexamethasone Treatment on the Hematological and Histological Parameters of Mice Following Experimental Bacterial Infection},
    journal = {Journal of Animal and Veterinary Advances},
    volume = {2},
    number = {4},
    pages = {231-236},
    year = {2003},
    issn = {1680-5593},
    doi = {javaa.2003.231.236},
    url = {https://makhillpublications.co/view-article.php?issn=1680-5593&doi=javaa.2003.231.236},
    author = {Salmah Ismail,Son Radu,Khalifah Sidek,Mohd Azhar Arifffin,Mohammad Nazmul Hasan Maziz,Irwan Hamzah and},
    keywords = {},
    abstract = {There are four groups of balb/c mice with each of it consists of 6 animals. Group 1, 2 and 3 were injected with dexamethasone daily for three days and experimentally infected with Pasteurella multocida, Escherichia coli harboring a recombinant plasmid ABA392 and Staphylococcus aureus respectively. Whereas, group four serve as control. At 24, 48 and 72 hours post-infection a marked increase in total leucocytes counts while differential leucocytes count revealed a marked increase in neutrophils and decrease in lymphocytes and monocytes in all dexamethasone-treated animals and was more predominant in group 1 and 2 post infection in all animals. At 72 hours post-infection, the histological examination reveals haemorrhagic (hemorrhagic septicaemia) features of lungs in dexamethasone-treated mice and infected with P. multocida and the recombinant plasmid ABA392 but not with the dexamethasone-treated and infected with S. aureus indicate that recombinant plasmid ABA392 may harbor a sequence that may code for virulent factor of Pasteurella multocida.}
    }