International Journal of Tropical Medicine
ISSN: Online 1818-779XISSN: Print 1816-3319
Abstract
Seminoma is a malignant germ cell tumor most commonly arising in the testes, typically affecting young males. Although seminoma is highly treatable with a survival rate above 95% in early stages, distant metastasis, particularly to the brain and lungs, is extremely rare. This case report highlights a rare instance of seminoma with both brain and lung metastases in an 18‐year‐old male. An 18‐year‐old male presented with chest pain, hemoptysis and severe headaches. Physical examination revealed scrotal swelling and normal genitalia. Investigations, including CT of the chest and brain, identified multiple necrotic lung nodules and hemorrhagic brain metastases. A scrotal ultrasound confirmed a testicular tumor and the patient underwent radical orchidectomy. Histopathology confirmed the diagnosis of seminoma. Five days post‐surgery, the patient developed altered sensorium and brain imaging revealed metastatic lesions with a midline shift. Management and Outcome: The patient received a multidisciplinary approach to treatment, including BEP (Bleomycin, Etoposide, Cisplatin) chemotherapy and supportive care for brain metastasis. The brain metastases were initially managed with steroids to reduce cerebral edema. The patient demonstrated improvement after chemotherapy, with partial remission of lung metastasis and stabilization of neurological symptoms. This case represents a rare and aggressive form of seminoma with brain and lung metastasis, highlighting the importance of early detection and individualized treatment strategies. Brain metastases in seminoma are extremely rare and require a multidisciplinary approach, including surgery, chemotherapy and potentially radiotherapy. Long‐term follow‐up is crucial in managing such rare presentations. Seminoma, although highly treatable, can metastasize to distant organs such as the brain and lungs, as seen in this rare case. Among young males with testicular tumors, brain metastasis should be considered, especially when neurological symptoms arise. Early intervention and aggressive treatment are key to improving patient outcomes in metastatic seminoma.
How to cite this article:
Katkam Shravani, Muramreddy Sreepoojitha, Kanchi Lavanya, Bobbala Naga Naveen and Vangapalli Gnana Deepika. A Rare Case of Seminoma with Brain Metastasis and Lung Metastasis.
DOI: https://doi.org/10.36478/10.36478/makijtm.2024.4.31.34
URL: https://www.makhillpublications.co/view-article/1816-3319/10.36478/makijtm.2024.4.31.34