S. Mushayabasa,
Impact of Vaccines on Controlling Typhoid Fever in Kassena-Nankana District of Upper East Region of Ghana: Insights from a Mathematical Model,
Journal of Modern Mathematics and Statistics,
Volume 5,Issue 2,
2011,
Pages 54-59,
ISSN 1994-5388,
jmmstat.2011.54.59,
(https://makhillpublications.co/view-article.php?doi=jmmstat.2011.54.59)
Abstract: Vaccination is an important prevention and control measure for the spread of typhoid fever. In this study, we develop a simple mathematical model to explore the impact of vaccination on the transmission dynamics of typhoid fever in Kassena-Nankana district of Upper East region of Ghana. Analytical results of the model show that the quantities Rv and R0 which represent the vaccine-induced reproduction number and the no vaccine induced reproduction number, respectively provide threshold conditions that determine the prevalence of typhoid fever in a community. These threshold conditions can be used to gain important insights into the impact of vaccination on controlling typhoid fever. Numerical results have been provided to illustrate the analytical findings.
Keywords: Salmonella paratyphi;typhoid fever;vaccines;reproductive number;Zimbabwe;stability