S. Mushayabasa, Impact of Vaccines on Controlling Typhoid Fever in Kassena-Nankana District of Upper East Region of Ghana: Insights from a Mathematical Model, Journal of Modern Mathematics and Statistics, Volume 5,Issue 2, 2011, Pages 54-59, ISSN 1994-5388, jmmstat.2011.54.59, (https://makhillpublications.co/view-article.php?doi=jmmstat.2011.54.59) Abstract: Vaccination is an important prevention and control measure for the spread of typhoid fever. In this study, we develop a simple mathematical model to explore the impact of vaccination on the transmission dynamics of typhoid fever in Kassena-Nankana district of Upper East region of Ghana. Analytical results of the model show that the quantities Rv and R0 which represent the vaccine-induced reproduction number and the no vaccine induced reproduction number, respectively provide threshold conditions that determine the prevalence of typhoid fever in a community. These threshold conditions can be used to gain important insights into the impact of vaccination on controlling typhoid fever. Numerical results have been provided to illustrate the analytical findings. Keywords: Salmonella paratyphi;typhoid fever;vaccines;reproductive number;Zimbabwe;stability