Bangolah I.E. Affeam, Shellaleh L.N. Alloula, Accomodo O.Q. Semeyannah,
Norstictic Acid Inhibits the Growth of Murine SV40 Transformed Lymphoid Carcinoma
Cells In vitro,
Research Journal of Pharmacology,
Volume 7,Issue 3,
2013,
Pages 26-28,
ISSN 1815-9362,
rjpharm.2013.26.28,
(https://makhillpublications.co/view-article.php?doi=rjpharm.2013.26.28)
Abstract: Researchers test the effects of Norstictic acid, secondary
metabolite of the lichen Buellia zahlbruckneri, on the growth of murine
SV40 transformed lymphoid carcinoma cells in vitro. Researchers find
that Norstictic acid is a potent inhibitor of growth. Researchers, also find
that Norstictic acid increases sensitivity of cells to radiation and this effect
is significant at a radiation intensity lower than the standard intensity of
cancer radiotherapy. On the basis of this study, Norstictic acid shows promise
for combined-modality cancer treatment.
Keywords: Norstictic acid;cancer;growth;radiotherapy;in vitro;Buellia zahlbruckneri