Syamsudin , Inawati , Hendig Winarno , The Effect of Inai (Lawsonia inermis Linn) Leaves Extract on Blood Sugar Level: An Experimental Study, Research Journal of Pharmacology, Volume 2,Issue 2, 2008, Pages 20-23, ISSN 1815-9362, rjpharm.2008.20.23, (https://makhillpublications.co/view-article.php?doi=rjpharm.2008.20.23) Abstract: This is a study of the effect of Inai (Lawsonia inermis Linn) leaves extract on glucose, total cholesterol and triglyceride of blood of mice which was induced by alloxan of 70 mg kg 1 BW. Inai leaves extract was obtained by the percolation of dried inai leaves using 70% ethanol. Sample treatments were done at day of 0, 3, 7 and 14th after the mice underwent the hyperglycaemic condition. The results showed that the feeding of 0.8 g kg 1 BW of inai extract decreased the glucose concentration from 194 mg dL 1 to normal condition after the 14th day. A similar result occured on total cholesterol concentration in which the total cholesterol concentration decreased from 148.9-55.3 mg dL 1 and triglyceride concentration decreased from 225.7-76.9 mg dL 1. Keywords: Lawsonia inermis;diabetes mellitus;total cholesterol;triglyceride