Bekaydar K.  Nurmashev, Oleg V.  Galimov, Bakhytzhan D.  Seksenbayev, Rassim A.  Kerimov, Murat E.  Zhanteyev, 
    Colorectal Cancer and Ethnic Groups in Kazakhstan. A Retrospective
Study of 709 Cases,
    Research Journal of Medical Sciences,
    Volume 11,Issue 2,
    2017,
    Pages 114-118,
    ISSN 1815-9346,
    rjmsci.2017.114.118,
    (https://makhillpublications.co/view-article.php?doi=rjmsci.2017.114.118)
    Abstract: Colorectal cancer keeps an upward incidence trend worldwide. Many studies show that colon cancer
is preventable disease in most cases: 70% of them might be avoided by lifestyle and diet changes. Despite the
globalization processes, ethnic mode of life at a certain extent forms lifestyle and nutrition habits of the
Kazakhstan population. Disparities in people traditions may be reflected in the features of colorectal cancer
development among different ethnic groups of the studied areas. The aim of the study was to assess
associations between colorectal cancer and major ethnic groups residing in Kazakhstan. This was a
retrospective study in which we analyzed all primary cases of colorectal cancer registered in 2013 year. All
records were provided by the regional oncology centers in 4 regions of the republic. Eventually, a cohort of
709 cases was formed. Each record of the disease was analyzed in terms of ethnicity, age, gender, disease stage
and tumor location. A significant association between colorectal cancer and ethnicities was found in the patient
group (<i>X</i><sup>2</sup><sub>(2)</sub> = 213.5, p&lt;0.001): in Russians, the disease was registered 1.9 time as many as it was expected. No
(2)
associations between colorectal cancer and tumor location were found for any ethnic group. The study
suggests a significant association between the disease and the ethnic groups residing in Kazakhstan. Nutrition
and lifestyle tendencies might play rather important role in this matter than any biological signs. We suggest
a case-control study should be conducted for further investigation of revealed relationship.
    Keywords: Colorectal cancer;globalization;nutrition;ethnicity;tendencies