Avinash Mane, Mahendra Patil, S.R. Upadhey, Serous Effusions: A Clinicopathological Study, Research Journal of Medical Sciences, Volume 9,Issue 6, 2015, Pages 319-322, ISSN 1815-9346, rjmsci.2015.319.322, (https://makhillpublications.co/view-article.php?doi=rjmsci.2015.319.322) Abstract: he term serous effusion refers to the fluid collected in the three serous cavities namely-pleural, peritoneal and pericardial. Various disease processes may disturb this equilibrium and can lead to accumulation of larger amount of fluids, leading to effusion. Depending upon the disease process the nature and composition of fluid may vary. Fluid tapping, a minimally invasive diagnostic as well as therapeutic procedure with serous fluid examination is a well-established method for determining the etiology of effusions. In case of clinical suspicion of malignant effusion, typing of fluid into exudate or transudate and wet mount preparation for abnormal cells may be done before examination of fixed smears for malignant cells as we did not find any transudative fluid positive for malignancy. Keywords: Effusions;fluid;clot;transudate or exudate;pleural