Manmohan Singhal, Parul Srivastava, Effect of Concanavalin A on IL-2 Expression from Lymph Node Cells, Research Journal of Medical Sciences, Volume 7,Issue 4, 2013, Pages 102-109, ISSN 1815-9346, rjmsci.2013.102.109, (https://makhillpublications.co/view-article.php?doi=rjmsci.2013.102.109) Abstract: Lymph nodes are organ and widely distributed in different parts of the body where innate immune responses lead to acquired immunity where autoreactive lymphocytes first encounter tissue-specific self-antigens and are either tolerized or activated. Lymph nodes respond well to mitogens (Concanavalin A) and alloantigens and stimulate the T-lymphocyte proliferation and activate the IL-2 surface receptor for expression of IL-2 in vitro. The present review aimed to discuss the pattern of expression of IL-2 and the effect of Concanavalin A in lymph nodes. Keywords: Lymph;mitogen;interleukin;lymphocyte;immune system