Yakup  Kumtepe, Kadir  Cetinkaya, 
    Management and Patient Selection for BRCA Genetic Testing to Identify Women at Increased Risk for Breast and Ovarian Cancers: A Review,
    Research Journal of Medical Sciences,
    Volume 6,Issue 2,
    2012,
    Pages 83-86,
    ISSN 1815-9346,
    rjmsci.2012.83.86,
    (https://makhillpublications.co/view-article.php?doi=rjmsci.2012.83.86)
    Abstract: Cancer caused by a mutated gene is a hereditary cancer rather than a sporadic cancer. Women who have inherited mutations in the <I>BRCA1</I> or <I>BRCA2</I> genes have substantially elevated risks of breast and ovarian cancer. Further genetic risk assessment is recommended for women who have &gt;20-25% chance of having an inherited predisposition to breast or ovarian cancer. Women with harmful mutations in either BRCA1 or BRCA2 have risk of breast cancer that is about 5 times the normal risk and a risk of ovarian cancer that is about 10-30 times normal. Mutation carriers have various options including extensive and regular surveillance, chemoprevention and risk-reducing surgery.
    Keywords: Brest cancer;BRCA gene mutation;surveillance;risk;women;Turkey