A.O. Aliyu, J.N. Nwabueze,
Studies on the Complexation of Cobalt (II) with Isonicotinohydroxamic Acid and It’s Microbial Sensitivity,
Research Journal of Medical Sciences,
Volume 3,Issue 5,
2009,
Pages 170-174,
ISSN 1815-9346,
rjmsci.2009.170.174,
(https://makhillpublications.co/view-article.php?doi=rjmsci.2009.170.174)
Abstract: A spectroscopic investigation of the reaction of Co2+ with isonicotinohydroxamic acid (INHAH) in aqueous solution of I = 0.1 moL dm-3 at 25°C reveals the sole formation of 1: 2 complex, spectral and magnetic studies on the isolated complex indicate an octahedral geometry with an O, N coordination mode for the ligand. Microbial sensitivity test on eight microorganism shown an enhanced antimicrobial activity for the complex relative to the free ligand.
Keywords: Hydroxamic acid;spectroscopic investigations;microbial activity;cobalt (II);octhedral geometry