H. Noorul Ayesha, Alex Arthur Edwards, Surgical Management of Peritonitis Secondary to Hollow Viscus Perforation a Prospective Observational Study, Research Journal of Medical Sciences, Volume 19,Issue 4, 2025, Pages 126-128, ISSN 1815-9346, makrjms.2025.4.126.128, (https://makhillpublications.co/view-article.php?doi=makrjms.2025.4.126.128) Abstract: Peritonitis requires emergency surgical intervention and is associated with significant morbidity and mortality rates. The presence of pneumo bperitoneum on radiographs is confirmatory of viscus perforation. The definitive diagnosis should be arrived at the shortest period of time with available investigations. Cases of peritonitis secondary to hollow viscus perforation undergoing emergency laparotomy was assessed for the site of perforation, its pathological condition and the amount of peritoneal contamination. Depending on the site of perforation and pathological condition, appropriate procedure will be adopted for its management, that includes omental patch closure, simple closure, open appendectomy, resection anastomosis and loop ileostomy. Postoperatively patients was examined for the development of any complications. The procedure performed intraoperatively depended upon the operating surgeon and the site of perforation noted in situ. Study duration was between June 2022 to September 2023 , 50 patients who were older than 18 years with primary unilateral uncomplicated inguinal hernia, who presented for operation in the department of General surgery, Sree mookambika college of medical sciences Kulasekharam were considered eligible for the study. Each patient presenting with peritonitis was examine thoroughly after taking a detailed history. The diagnosis was confirmed by history, clinical features and erect abdominal X-ray. Cases of peritonitis secondary to hollow VISCUS perforation undergoing emergency laparotomy was assessed for the site of perforation, its pathological condition and the amount of peritoneal contamination. Whenever there was a suspicion of peritonitis or the radiograph was inconclusive, it was proceeded with computed tomography. It was done in 35% of the cases and the findings included the presence of free fluid in 27% cases, free air in 19% cases, fat stranding in 14% cases and air pockets in 5% cases. Free air was noted in 16% cases of duodenal perforation because the radiograph was inconclusive in these cases. All the cases diagnosed with fat stranding had appendicular perforation intraoperatively. All the cases of perforation were initially stabilized and proceeded with laparotomy, since most of the cases had duodenal perforation, omental patch repair was done in all these cases. Keywords: Ileal perforations; omental patch; peritonitis