Shebel A. AlSabbah, Mohammad A. Al-Khedher, Tariq M. Younes, Evaluation of Multiregional Fuzzy-Based pH Cascade Control with ANFIS-Based pH Observer, Research Journal of Applied Sciences, Volume 7,Issue 2, 2012, Pages 60-65, ISSN 1815-932x, rjasci.2012.60.65, (https://makhillpublications.co/view-article.php?doi=rjasci.2012.60.65) Abstract: In pH reactors, determination and control of pH is a common problem concerning chemical-based industrial processes due to the non-linearity observed in the titration curve. The researchers introduced a modified multiregional Fuzzy-Based Control System to overcome the complexity of precise control of pH. In order to compensate for the experimental inaccuracies in measurements of pH in-situ values; an observer for pH is implemented using Adaptive Neuro-Fuzzy Inference System (ANFIS). The pH control approach and ANFIS-based observer are integrated in a nonlinear cascade structure to ensure the dynamic modifications and stability enhancement. The cascade structure is designed using a multiregional fuzzy PI controller in the master loop and a Wiener Model-based fuzzy proportional controller as a slave one. The Multiregional Fuzzy Cascade Control (MFCC) structure is developed to implicate the three main regions of the titration curve. Keywords: Titration process;cascade structure;multiregional fuzzy;ANFIS;pH observer;Jordan