Takahisa  Yamada, Bin  Tong, Kaifeng  Wu, Seiki  Sasaki, Youji  Muramatsu, Takeshi  Ohta, Hiroyuki  Kose, 
    Possible Association of Single Nucleotide Polymorphism in the Myosin Heavy Chain 1 Gene with Growth-Related Trait in Japanese Black Beef Cattle,
    Journal of Animal and Veterinary Advances,
    Volume 13,Issue 1,
    2014,
    Pages 41-44,
    ISSN 1680-5593,
    javaa.2014.41.44,
    (https://makhillpublications.co/view-article.php?doi=javaa.2014.41.44)
    Abstract: Growth performance as well as marbling is the main breeding 
  objectives in Japanese Black cattle, the major beef breed in Japan. The Myosin 
  Heavy chain 1 (<I>MYH1</I>) gene is reported to encode an isoform of myosin 
  heavy chain in type I fiber of skeletal muscle and has been previously shown 
  to be located within genomic region of a quantitative trait locus for growth-related 
  trait. The earlier study detected a Single Nucleotide Polymorphism (SNP), referred 
  to as g.29850738G&gt;A in the promoter regionof the <I>MYH1</I> gene which exhibited 
  significantly different allelic distribution between Japanese Black sires with 
  extremely high predicted breeding value and the sires with extremely low one 
  for Carcass Weight (CWT) and Rib Thickness (RT) in a preliminary study. In the 
  present study, researchers analyzed the effect of the MYH1g.29850738G&gt;A SNP 
  genotypes on the growth-related carcass trait in Japanese Black beef cattle. 
  The SNP was significantly associated with RT and marginally associated with 
  CWT (p = 0.016 and 0.069, respectively) in experiment 1 using 101 Japanese Black 
  sires. Further, a slight trend of significance for CWT and RT was observed for 
  the SNP in experiment 2 using 745 paternal half-sib progeny steers from 2 sires 
  homozygous for G allele at the g.29850738G&gt;A in Japanese Black beef cattle. 
  These findings suggest possible effect of the g.29850738G&gt;A SNP on the growth-related 
  trait in Japanese Black beef cattle. The MYH1 SNP may be useful for effective 
  marker-assisted selection to increase the beef productivity in Japanese Black 
  beef cattle.
    Keywords: Association;beef cattle;growth-related trait;Japanese Black breed;MYH1;single nucleotide polymorphism