Xing  Jin-Ming, Yuan Wen-Xue  , Zhang Zhi-Cheng  , Chen Shuai  , 
    Anti-Fatigue Activity of Crude Saponins from <I>Panax quinquefolium</I>,
    Journal of Animal and Veterinary Advances,
    Volume 12,Issue 5,
    2013,
    Pages 584-588,
    ISSN 1680-5593,
    javaa.2013.584.588,
    (https://makhillpublications.co/view-article.php?doi=javaa.2013.584.588)
    Abstract: The present study was carried out to investigate anti-fatigue 
  activity of Crude saponins from <I>Panax quinquefolium </I>(CPQS) in mice. The 
  animals were randomly divided into four groups: control (distilled water); 50 
  mg kg<SUP>-1</SUP> CPQS; 100 mg kg<SUP>-1</SUP> CPQS and 200 mg kg<SUP>-1</SUP> 
  CPQS. Distilled water or CPQS were orally administered for consecutive 28 days. 
  The 28 days later, forced swimming test was performed and then fatigue-related 
  biochemical parameters including blood lactic acid, serum urea nitrogen, liver 
  glycogen and muscle glycogen were detected. The results showed that CPQS could 
  prolong the swimming to exhaustion time of mice as well as increasing the liver 
  and muscle glycogen contents but decrease the blood lactic acid and serum urea 
  nitrogen levels. Therefore, the present study demonstrated that CPQS possessed 
  anti-fatigue activity.
    Keywords: Anti-fatigue activity;crude saponins from Panax quinquefolium;forced swimming test;mice;liver glycogen