Gang Duan, Feiyan Dai, Wengui Li, Libo Gao, Gefen Yin, Gang Feng, Weibing Bai,
Phylogenetic Analysis of the ORF2 Genes of Porcine Circovirus 2 Strains Isolated in Yunnan Province, China,
Journal of Animal and Veterinary Advances,
Volume 12,Issue 1,
2013,
Pages 1-5,
ISSN 1680-5593,
javaa.2013.1.5,
(https://makhillpublications.co/view-article.php?doi=javaa.2013.1.5)
Abstract: The ORF2 genes of 10 isolated Porcine Circovirus type
2 (PCV2) strains in Yunnan Province of China were sequenced, analyzed and further
compared with the sequences of 24 strains retrieved from GenBank. The results
showed that the ORF2 genes of the 10 strains in Yunnan Province shared
sequence identity of 98.7-100.0% on nucleotide acid level and of 96.2-100.0%
on amino acid level. Moreover, Yunnan strains and the other 24 strains retrieved
from GenBank shared 91.0-99.7% nucleotide and 80.3-97.4% amino acid sequence
similarity. Based on the phylogenetic tree analysis, these strains could be
divided into five genotypes (PCV2a-PCV2e) and all the Yunnan strains fall into
PCV2b genotype. Compared with other PCV2b strains, nine point mutations of amino
acid residues were identified only in Yunnan strains which might be essential
for controlling PCV2 infection in Yunnan Province, China.
Keywords: Porcine circovirus type 2;ORF2 gene;phylogenetic analysis;GenBank;Yunnan Province;China