Lixin  Du, Lingyang  Xu, Fuping  Zhao, Hangxing  Ren, Jian  Lu, Li  Zhang, Caihong  Wei, 
    AGPBSim: Gene Pyramiding Breeding in Animals from Perspective of Synthetic Biology,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 7,
    2012,
    Pages 933-938,
    ISSN 1680-5593,
    javaa.2012.933.938,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.933.938)
    Abstract: AGPBSim (Animal Gene-Pyramiding Breeding Simulation) is an individual-based, genetical information integrated simulation program. It was developed to investigate gene-pyramiding breeding given base population sizes, initial allele frequencies and selection strategies. The process of gene-pyramiding breeding was measured using population hamming distance, superior genotype frequency and average phenotypic values. AGPBSim is high flexible at various levels: four cross schemes and three selection strategies and trait architecture using various genotype-phenotype models were integrated in gene pyramiding breeding simulation. The GUI design of AGPBSim can facilitate design of gene-pyramiding breeding strategies by performing virtual breeding simulation on this platform.
    Keywords: Breeding;allele frequencies;population;architecture;gene-pyramiding;platform