Hai  Fang, Qiuyue  Wang, Qiumei Shi  , Yanying Zhang  , Wei Yao  , Cuizhen Chen  , Guangping Gao  , Donglin Zhang  , 
    Detection Class I Integron of Multidrug Resistace Pathogenic Salmonella from Chicken in Hebei Province, China,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 6,
    2012,
    Pages 742-745,
    ISSN 1680-5593,
    javaa.2012.742.745,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.742.745)
    Abstract: Antimicrobial resistance test of 59 Salmonella isolated from chicken was done by K-B method. The drug-resistance rate of oxacillin, tetracycline, erythromycin, penicillin G, gentamicin was 74.6, 64.4, 52.5, 47.5 and 37.3%, respectively. Most of the isolates were multidrug resistance and the rate was 81.36% (48/59). Among the total of the multidrug resistance isolates, the rate of resistance to three, four and five drugs was 45.76% (27/59), 23.73% (14/59) and 11.86% (7/59). PCR and DNA sequencing were used for screening and characterization of class I integrons. As a result, the detection rate of class I integron was 40.68% (24/59) and among these 48 isolates which had been proven multidrug-resistant, the detection rate of class I integron was 50% (24/48). Class I integron PCR positive isolates rate of multidrug-resistance was 100% (24/24). Results show that the class I integron has the relationship with multidrug resistance.
    Keywords: Salmonella;class I integron;multidrug resistance;detection;multidrug;China