A.I. Almubarak,
Evaluation of Intravenous Administration of Doxapram Prior to Xylazine Sedation in Camels (Camelus dromedarius),
Journal of Animal and Veterinary Advances,
Volume 11,Issue 23,
2012,
Pages 4455-4459,
ISSN 1680-5593,
javaa.2012.4455.4459,
(https://makhillpublications.co/view-article.php?doi=javaa.2012.4455.4459)
Abstract: The effects of doxapram on respiratory rate, heart rate, Arterial
Blood Pressure (ABP) and some haematology and biochemistry parameters were carried
out on six camels in two periods. In the first period, all camels received Intravenous
(IV) 0.2 mg kg-1 xylazine while in the second period, same camels
received IV 0.4 mg kg-1 doxapram, followed 10 min later by IV 0.2
mg kg-1 xylazine. Cardiopulmonary measurements were taken at baseline
and were further recorded at 10, 20, 30, 40, 50 and 60 min after treatment in
both periods. Mean respiratory rate, heart rate and ABP measurements decreased
significantly after xylazine in the first period. Mean respiratory rate in the
second period increased significantly at 10 min while systolic ABP increased
significantly at 30 min when compared with first period. Mean heart rate decreased
significantly at 20 min in the second period when compared with first period.
There was a significant differences between the two periods in some measured
haematological and biochemical parameters. Doxapram was useful to increase respiratory
rate and ABP in xylazine sedated camels. Higher doses of doxapram needed further
investigation in camels.
Keywords: Camel;doxapram;xylazine;analeptic;sedation;haematology;biochemistry