Shuang Xu, Xing-Jun Xu, Jian-Wei Lv, Shu-Li Shao, Tian-Fei Yu, Ming Li, Genetic Variation Analysis of TGEV Spike Protein Antigenic Sites, Journal of Animal and Veterinary Advances, Volume 11,Issue 3, 2012, Pages 361-363, ISSN 1680-5593, javaa.2012.361.363, (https://makhillpublications.co/view-article.php?doi=javaa.2012.361.363) Abstract: The spike genes of 22 different TGEV strains were selected from GenBank and analysed by the Bioinformatics analysis software. The results showed that the A and C antigen sites are more conservative than B and D antigen sites. The results could establish the rationale for preparing vaccine of epitopes and diagnostic reagent. Keywords: molecular characteristic;epitope;spike protein;TGEV;China