Mojtaba  Lotfi, Mohammad  Taghi Beigi Nassiri, Hedayatollah  Roshanfekr, Jamal  Fayazi, 
    Polymorphism of Ovar-DRB1 Second Exon with PCR-RFLP Technique in Arabi Sheep Population of Khuzestan Province,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 3,
    2012,
    Pages 343-345,
    ISSN 1680-5593,
    javaa.2012.343.345,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.343.345)
    Abstract: Major Histocompatibility Complex (MHC) plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. The best-characterized genetic control of disease resistance and immune response in animals are associated with MHC. Therefore in this study polymorphism of ovar-DRB1 in DNA samples of 111 heads Arabi sheep using Polymerase Chain Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) method was examined. Identities of 18 different patterns and 8 distinct DRB1 alleles among Arabi sheep have been determined. There is not deviation in <I> Ovar-DRB1</I> gene from Hardy-Weinberg equilibrium in this population results showed. Obtained results have revealed that the exon 2 region of ovar-DRB1 was highly polymorphic on Arabi sheep.
    Keywords: Arabi sheep;MHC;ovar-DRB1;PCR-RFLP;Khuzestan province;Iran