Takahisa Yamada  , Hideki  Tanomura, Youji Muramatsu  , Takuji Yamamoto  , Takeshi Ohta  , Hiroyuki Kose  , 
    Association of Single Nucleotide Polymorphism in Pancreatic Lipase Gene with Growth-Related Traits in Japanese Black Beef Cattle,
    Journal of Animal and Veterinary Advances,
    Volume 11,Issue 9,
    2012,
    Pages 1346-1349,
    ISSN 1680-5593,
    javaa.2012.1346.1349,
    (https://makhillpublications.co/view-article.php?doi=javaa.2012.1346.1349)
    Abstract: Growth performance as well as marbling is the main breeding objectives in Japanese Black cattle, the major beef breed in Japan. Researchers have recently reported that a Single Nucleotide Polymorphism (SNP) referred to as rs41648172 in intron 6 region of the Pancreatic Lipase (<I>PNLIP</I>) gene was associated with marbling in Japanese Black beef cattle with the T allele being associated with a high level of marbling. The PNLIP is known to be involved in the hydrolysis of dietary triglycerides to fatty acids which is essential for the intestinal absorption of long-chain triglyceride fatty acids. Thus, the PNLIP was considered as a functional candidate for the gene responsible for growth performance. In this study, researchers analyzed the effect of the PNLIP rs41648172 SNP genotypes on the growth-related traits in Japanese Black beef cattle. The SNP was associated with carcass weight, rib eye area, rib thickness and daily gain in the experiment using 367 paternal half-sib progeny steers from a sire homozygous for C allele at the rs41648172 in Japanese Black beef cattle. The SNP was also associated with carcass weight, rib eye area and daily gain in the experiment using 587 paternal half-sib progeny steers from a sire homozygous for T allele at the rs41648172 in Japanese Black beef cattle. These findings suggest possible effect of the rs41648172 on the growth-related traits in Japanese Black beef cattle. The PNLIP SNP polymorphism may be useful for effective marker-assisted selection to increase the beef productivity in Japanese Black beef cattle.
    Keywords: Association;beef cattle;growth-related trait;Japanese Black breed;single nucleotide polymorphism;PNLIP