Song-Jia Lai, Wei Wang, Xiao-Mao Guo, Jian Wang, Product Fat-1 Transgenic Simmental Crossbred Cattle Endogenously Synthesizing Omega-3 Polyunsaturated Fatty Acids Using OSM, Journal of Animal and Veterinary Advances, Volume 11,Issue 7, 2012, Pages 1041-1045, ISSN 1680-5593, javaa.2012.1041.1045, (https://makhillpublications.co/view-article.php?doi=javaa.2012.1041.1045) Abstract: Meat products normally contain low omega-3 fatty acids and high ratio of n-6/n-3 fatty acids may contribute to the prevalence of many diseases. In order to obtained in such beef with high levels of omega-3 fatty acids will be more healthy to meet people’s diet, researchers generated the fat-1 transgenic simmental crossbred cattle expressing the Caenorhabditis elegans c fat-1 gene encoding an omega-3 fatty acid desaturase that converts omega-6 to omega-3 fatty acids and the gene is absent in mammals. In this study, researchers successful product the embryo of fat-1 transgenic simmental crossbred cattle using OSM. The results of Western Blotting and fluoroscopic examination have proved that the fat-1 gene has been into genome of clone embryo and translated into proteins which could be used to embryo transfer. Keywords: OSM;fat-1;omega-3 fatty acid desaturase;omega-3 fatty acids;embryo;embryo