Yucel Basimoglu  Koca, Serdar  Koca, Beyhan  Gurcu, Sukran  Yildiz, 
    Histopathological and Genotoxic Effects of Pollution on <I>Anguilla anguilla</I> in the Gediz River (Turkey),
    Journal of Animal and Veterinary Advances,
    Volume 9,Issue 23,
    2010,
    Pages 2890-2899,
    ISSN 1680-5593,
    javaa.2010.2890.2899,
    (https://makhillpublications.co/view-article.php?doi=javaa.2010.2890.2899)
    Abstract: The aim of the present study was to determine heavy metal 
  accumulation in water, sediment and some tissues of <I>Anguilla ang</I>uilla 
  along with determining histopathological and genotoxic effects of accumulation 
  on these tissues by using light microscopy. Water, sediment and fish tissue 
  samples taken from different sites of 3 different study areas were studied and 
  the order of accumulation of metals was Fe&gt;Pb&gt;Mn&gt;Co&gt;Zn&gt;Ni&gt; 
  Cr&gt;Cu&gt;Cd in water, Fe&gt;Co&gt;Mn&gt;Pb&gt;Zn&gt;Ni&gt;Cr&gt;Cu&gt;Cd 
  in sediment and Cd&gt;Mn&gt;Cu&gt;Cr&gt;Ni&gt;Fe&gt;Zn&gt;Co&gt;Pb, Cd&gt;Pb&gt;Ni&gt;Cr&gt;Mn&gt;Cu&gt;Fe&gt;Co&gt;Zn 
  and Cr&gt;Ni&gt;Zn&gt;Cd&gt;Pb&gt;Mn&gt;Cu&gt;Fe&gt;Co in liver, muscle and 
  gill of fish, respectively. In histopathological studies, a decrease in the 
  length of primary and secondary lamellae of gills, fusion in secondary lamellae, 
  cellular proliferation, clavate lamellae formation and necrosis were observed. 
  In liver tissue, dilation of sinusoid, increase in the number of erythrocytes, 
  ruptured hepatocytes, decrease in glycogen accumulation and vacuolization were 
  observed. In muscle tissue, necrosis, cellular dissolution and loss of striatation 
  in muscle fibers were found. It was observed that pollution of water had no 
  genotoxic effect on <I>Anguilla anguilla</I>.
    Keywords: micronucleus;Bioaccumulation;water;sediment;fish;histopatology