TY - JOUR T1 - Impact of Vaccines on Controlling Typhoid Fever in Kassena-Nankana District of Upper East Region of Ghana: Insights from a Mathematical Model AU - Mushayabasa, S. JO - Journal of Modern Mathematics and Statistics VL - 5 IS - 2 SP - 54 EP - 59 PY - 2011 DA - 2001/08/19 SN - 1994-5388 DO - jmmstat.2011.54.59 UR - https://makhillpublications.co/view-article.php?doi=jmmstat.2011.54.59 KW - Salmonella paratyphi KW -typhoid fever KW -vaccines KW -reproductive number KW -Zimbabwe KW -stability AB - Vaccination is an important prevention and control measure for the spread of typhoid fever. In this study, we develop a simple mathematical model to explore the impact of vaccination on the transmission dynamics of typhoid fever in Kassena-Nankana district of Upper East region of Ghana. Analytical results of the model show that the quantities Rv and R0 which represent the vaccine-induced reproduction number and the no vaccine induced reproduction number, respectively provide threshold conditions that determine the prevalence of typhoid fever in a community. These threshold conditions can be used to gain important insights into the impact of vaccination on controlling typhoid fever. Numerical results have been provided to illustrate the analytical findings. ER -