TY  - JOUR
T1  - Evaluation of Fungal Taxol Isolated from an Endophytic Fungus <I>Pestalotiopsis pauciseta</I>VM1 Against Experimentally Induced Breast Cancer in Sprague Dawley Rats
AU - Muthumary, J. AU - Thirunavukkarasu, S.V. AU - Vennila, R. 
JO  - Research Journal of Pharmacology
VL  - 4
IS  - 2
SP  - 38
EP  - 44
PY  - 2010
DA  - 2001/08/19
SN  - 1815-9362
DO  - rjpharm.2010.38.44
UR  - https://makhillpublications.co/view-article.php?doi=rjpharm.2010.38.44
KW  - Pestalotiopsis pauciseta
KW  -Sprague Dawley rats
KW  -7
KW  - 12 dimethyl benz (a) anthracene
KW  -breast cancer
KW  -fungal taxol
AB  - The present study was carried out for chemopreventive effect of fungal taxol derived from an endophytic fungus, <I>Pestalotiopsis pauciseta</I> VM1 isolated from a medicinal plant <I>Tabebuia pentaphylla</I> Hemsl. The biochemical parameters like blood urea, serum uric acid, creatinine, haemoglobin, protein, tryglycerides, total cholesterol and phospholipids were estimated in control and experimental groups. Based on the results, the fungal taxol were found to be best against 7, 12 dimethyl benz (a) anthracene induced mammary tumors in Sprague Dawley rats.
ER  -