TY  - JOUR
T1  - Antibacterial Assays of Malaysian Medicinal Plant <I>Polygonum minus</I>
Using Different Extraction Methods
AU - Al-Haj, Nagi A. AU - Hassan, Khadija Zedan AU - Alabed, Alabed Ali A. AU - Al Mahdi, Abdullah Y. AU - Abdsalam, Rasheed AU - Albawani, Sami Mohammed 
JO  - Research Journal of Medical Sciences
VL  - 12
IS  - 1
SP  - 5
EP  - 11
PY  - 2018
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2018.5.11
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2018.5.11
KW  - Polygonum minus
KW  -antibacterial
KW  -ethanol extract
KW  -methanol extract
KW  -Bacillus subtilis
KW  -against
AB  - Medicinal plants and herbal preparations are gaining renowned interest in scientific communities
nowadays due to their reliable pharmacological actions and affordability to common people which makes them
effective in control of various diseases. The present study was aimed to evaluate the antibacterial activities of
aqueous, methanol and ethanol extracts against gram positive ad gram negative microorganism. The
combination effects of <i>Polygonum minus</i> methanol extracts with streptomycin sulfate against gram positive
<i>Bacillus subtilis</i> which showed 16.7% were synergy (2 out of 12 combinations), 16.7% were additive and (2 out
of 12 combinations), 66.7% were indifferent (8 out of 12 combinations). While, combination effects
between P. minus ethanol extract with streptomycin sulfate against <i>Bacillus subtilis</i> indicated that about 50%
(6 out of 12 combinations) were antagonistic, 16.67% (2 out of 12 combinations) were indifferent and 33.33%
(4 out of 12 combinations) were additive. The finding of this study concluded that gram-positive bacteria were
more susceptible than the gram-negative and the combination effects between <i>P. minus</i> ethanol extract with
streptomycin sulfate may lead to the development of a new and vital antimicrobial drugs against simultaneous
infections of gram positive and gram negative microorganism.
ER  -