TY - JOUR T1 - Biological Characteristics and Inhibition by Both Natural Agents and Antibiotics of Streptococcus Pyogenes AU - Enan, Gamal AU - Hamdy, Sara AU - Abdel-Shafi, Seham AU - Al-Mohammadi, Abdul-Raouf JO - Research Journal of Medical Sciences VL - 10 IS - 6 SP - 573 EP - 586 PY - 2016 DA - 2001/08/19 SN - 1815-9346 DO - rjmsci.2016.573.586 UR - https://makhillpublications.co/view-article.php?doi=rjmsci.2016.573.586 KW - Streptococcus pyogenes KW -classification KW -characterization KW -virulence KW -natural agents KW -diagnosi AB - In this review, the characteristics, classification, pathogenesis and diagnosis of Streptococcus pyogenes (S. pyogenes) infections are discussed. In addition, a list of antibiotics and natural agents necessary to inhibit S. pyogenes are listed herein. S. pyogenes is a group A beta-hemolytic Streptococcus. It is a facultative anaerobe, non-motile, non-sporing, spherical or ovoidal cocci. Many virulence factors are produced by S. pyogenes and are responsible for its infections such as streptolysin O, streptolysin S, streptococcal pyogenic exotoxin A and exotoxin C, streptokinase, hyaluronidase and C5a peptidase. Pathogenic causes of S. pyogenes are pharyngitis, impetigo, sepsis, erysipelas, Cellulities, puerperal fever, scarlet fever, rheumatic fever, glomerulonephritis and toxic shock syndrome. Serology, culturing and microscopic examination of S. pyogenes are the most important ways of diagnosis. The recent ways to inhibit S. pyogenes by natural agents (honey, essential oils, plant extracts) are also discussed. ER -