TY  - JOUR
T1  - Protective Effects of Recombinant Erythropoietin in Ischemia of the Retina: The Role of Mechanisms of Preconditioning
AU - Shabelnikova, Anna S. AU - Lutsenko, Vladimir D. AU - Pokrovskii, Mikhail V. AU - Peresipkina, Anna A. AU - Korokin, Mikhail V. AU - Gudyrev, Oleg S. AU - Pokrovskaia, Tatyana G. AU - Beskhmelnitsyna, Evgeniya A. AU - Hoshenko, Yuri A. 
JO  - Research Journal of Medical Sciences
VL  - 9
IS  - 4
SP  - 200
EP  - 203
PY  - 2015
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2015.200.203
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2015.200.203
KW  - Ischemia/reperfusion of the retina
KW  -recombinant erythropoietin
KW  -ischemic preconditioning
KW  -glibenclamidum
KW  -reperfusion
AB  - Recombinant erythropoietin in a dose 50 IU kg <SUP>&#150;1</SUP> under the condition of half-hour total ischemia of the retina followed by reperfusion showed a pronounced protective action, expressed in the prevention of reduction of the microcirculation, electroretinography amplitude and change of the morphometric values of layers thickness of the retina. The mechanisms of pharmacological preconditioning are important to cardioprotective effects that confirmed by reduction of its effects under the condition of K<SUB>ATP</SUB> channels blockade with glibenclamidum.
ER  -