TY  - JOUR
T1  - Therapeutic Effects of Atobeauty Cream in Atopic Dermatitis Model Mice Induced with DNCB
AU - Byung-Sung, Park AU - Sang-Oh, Park AU - Yong-Sik, Ahn AU - Chae-Min, Ryu AU - Ho-Yeol, Noh AU - Ga-Yeong, Noh 
JO  - Research Journal of Medical Sciences
VL  - 6
IS  - 2
SP  - 71
EP  - 76
PY  - 2012
DA  - 2001/08/19
SN  - 1815-9346
DO  - rjmsci.2012.71.76
UR  - https://makhillpublications.co/view-article.php?doi=rjmsci.2012.71.76
KW  - Atopic dermatitis
KW  -BALB/c mice
KW  -IgE
KW  -histamine
KW  -epidermis
AB  - This study has been performed to assess the anti-atopic efficiency in DNCB induced BALB/c to examine a therapeutic effect of Atobeauty cream which was provided by NJY Life Science Co., Ltd. on atopic dermatitis. Such BALB/c mice were provided by NJY Life Science Co., Ltd. The randomized complete block design was done by dividing 20 male mice with BALB/c into two groups of which the one group had 10 mice receiving no treatment as a control group and the other group had 10 mice receiving treatment with Atobeauty cream as a treatment group. When Atobeauty cream was applied to the mouse with severe atopic dermatitis 2 times a day for 6 days, it could be observed that its skin recovered to normal condition with the skin surface being clean and smooth without any horny tissue. It was found that each level of IgE and histamine in blood was significantly decreased by 57.80 and 59.41%, respectively in the Atobeauty cream treatment group (here in after, the treatment group), compared with the DNCB induced atopy control group (here in after, the control group (p<0.05). It was also identified that a mouse with atopic dermatitis to which Atobeauty cream was applied, recovered on the order of a normal mouse as its epidermis got to be softly formed with its surface thickness being even and its connective tissue got to be formed more uniformly.
ER  -