TY  - JOUR
T1  - Nutritional, Phytochemical Properties and Antibacterial Potential of Lantana
Camara Against Methicillin-Resistant <i>Staphylococcus aureus</i>
AU - Annan-Prah, Anthony AU - Yaw Effah, Clement AU - T.K.D. Dayie, Nicholas AU - Senyo Yao, Akorli 
JO  - Journal of Animal and Veterinary Advances
VL  - 17
IS  - 4
SP  - 95
EP  - 99
PY  - 2018
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2018.95.99
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2018.95.99
KW  - Lantana camara
KW  -nutritional
KW  -phytochemical
KW  -antibacterial
KW  -methicillin-resistant
KW  -Staphylococcus aureus
AB  - Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a major concern in clinical medicine due to
the importance of &beta;-lactams in the therapy of staphylococcal infections. MRSA strains have become a yardstick
for the test of new antibiotics because of their ability to respond to newly developed antibiotics. This research
was designed to investigate the antibacterial potential of <i>L. camara</i> leaves on MRSA isolated from pigs. Also,
Nutritional and phytochemical constituents were analysed, so as to hypothesise whether L. camara can serve
as feed component and simultaneously as prophylaxis against MRSA. Non-flowering <i>L. camara</i> leaves were
collected, washed and the extract was obtained through aqueous extraction. Nutritional parameters,
phytochemical constituents and Antibacterial potential of <i>L. camara</i> leaves were obtained using standard
procedures. MRSA isolates were obtained from the anterior nares of apparently clinically healthy pigs using
sterile cotton swabs. The result of proximate analysis using the AOAC method showed dry matter composition
of (23.2&plusmn;0.01%), crude fiber (20.9&plusmn;0.03%) crude protein (20.2&plusmn;0.02%), ether extract (4.3&plusmn;0.03%) and ash
(2.3&plusmn;0.03%). Quantification of the phytochemical component showed the concentration (mg/L) of the
following in the order: saponin>tannins>flavonoids>phenol>terpernoids for the oven dried-leaves and
saponin>tannins>terpernoids>flavonoids>phenol for the air dried-leaves. <i>Lantana camara</i> aqueous leaf extract
also had some bactericidal properties against MRSA isolates as it reduced the MRSA population size from
3.1&times;10<sup>5</sup> CFU/mL at day zero (0) to <1 CFU/mL in day 5. It can be concluded that <i>L. camara</i> leaves could be used
as feed component and at the same time as prophylaxis against MRSA infections.
ER  -