TY  - JOUR
T1  - Safety Assessment of a Turkey Herpes Virus Vector Newcastle Disease Vaccine in Chickens
AU - Zhao, Li-Li AU - Tang, Na AU - Zhang, Yuan-Yuan AU - Yu, Xiao-Hui AU - Zhang, Guo-Zhong 
JO  - Journal of Animal and Veterinary Advances
VL  - 13
IS  - 14
SP  - 897
EP  - 900
PY  - 2014
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2014.897.900
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2014.897.900
KW  - safety assessment
KW  -F gene
KW  -Newcastle disease virus
KW  -vaccine
KW  -HVT vector
AB  - A recombinant Herpes Virus of Turkeys (HVT) vaccine expressing the key protective antigen of Newcastle Disease Virus (NDV) could facilitate in the prevention and control of both Marek&#146;s Disease Virus (MDV) and NDV infections. The VECTORMUNE<SUP>&reg;</SUP> HVT NDV vaccine is a recombinant vaccine in which the <I>F</I> gene of a NDV lentogenic strain has been inserted into the HVT genome. In the current study, this vaccine was assessed for its safety in chickens. Based on clinical observations, gross pathological examinations, histopathological examinations, virus shedding and tissue distribution, the VECTORMUNE<SUP>&reg;</SUP> HVT NDV vaccine was determined to possess a high level of safety in chickens.
ER  -