TY - JOUR T1 - Biochemical Effects of the Herbicide Diclofop-Methyl Bioaccumulation in Freshwater Fish (Oreochromis niloticus) AU - Abd-Alrahman, Sherif H. AU - Elhalwagy, Manal E.A. AU - Gh. Farag, Ahmed A. AU - Kotb, Gamila A.M. JO - Journal of Animal and Veterinary Advances VL - 12 IS - 10 SP - 1016 EP - 1020 PY - 2013 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2013.1016.1020 UR - https://makhillpublications.co/view-article.php?doi=javaa.2013.1016.1020 KW - bioaccumulation KW -herbicide KW -Diclofop-methyl KW -tilapia fish KW -control AB - Chronic toxicity and bioacumulation of diclofop-methyl (Iloxan 36% EC) in tilapia fish (Oreochromis niloticus was investigated. Fish was exposed to two sub-lethal concentrations 1/10 (0.19 mg L-1, low concentration) and 1/3 (0.63 mg L-1, high concentration) of determined 96 h-LC50, 1.89 mg L-1 for 28 days. Results indicated that the bioaccumulation in whole fish was more than muscle. Results of biochemical parameters were indicated that alanine aminotransferases, alkaline phosphatase, acetyl-cholinesterase activities, albumin and glucose levels were increased significantly with both exposed concentrations comparing to control. However, significant increases were shown in aspartate aminotransferases and total protein levels with low concentration. On the other hand, high concentration caused significant increase in urea levels. Meanwhile, creatinine levels were decreased in both exposed concentrations. Noticeable changes in antioxidants biomarkers were recorded, a reduction in SH-protein level and an elevation in lipid peroxidation biomarker were recorded in plasma after treatment with two concentrations. ER -