TY - JOUR T1 - AGPBSim: Gene Pyramiding Breeding in Animals from Perspective of Synthetic Biology AU - Du, Lixin AU - Xu, Lingyang AU - Zhao, Fuping AU - Ren, Hangxing AU - Lu, Jian AU - Zhang, Li AU - Wei, Caihong JO - Journal of Animal and Veterinary Advances VL - 11 IS - 7 SP - 933 EP - 938 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.933.938 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.933.938 KW - Breeding KW -allele frequencies KW -population KW -architecture KW -gene-pyramiding KW -platform AB - AGPBSim (Animal Gene-Pyramiding Breeding Simulation) is an individual-based, genetical information integrated simulation program. It was developed to investigate gene-pyramiding breeding given base population sizes, initial allele frequencies and selection strategies. The process of gene-pyramiding breeding was measured using population hamming distance, superior genotype frequency and average phenotypic values. AGPBSim is high flexible at various levels: four cross schemes and three selection strategies and trait architecture using various genotype-phenotype models were integrated in gene pyramiding breeding simulation. The GUI design of AGPBSim can facilitate design of gene-pyramiding breeding strategies by performing virtual breeding simulation on this platform. ER -