TY - JOUR T1 - Fu Zi Prevent Extreme Cold Stress in Broilers Through Anti-Oxidative Activity AU - , Z.Y. Geng AU - , R.S. Jiang AU - Jin, S.H. AU - Chen, X.Y. JO - Journal of Animal and Veterinary Advances VL - 11 IS - 6 SP - 849 EP - 852 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.849.852 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.849.852 KW - nitric oxide KW -Radix aconiti laterlis preparata KW -extreme cold stress AB - Radix aconiti laterlis preparata (Fu Zi in Chinese), a Chinese traditional medicine has been widely used for Yang deficiency. Recent clinical studies have shown that Fu Zi could ameliorate stressed condition but the mechanisms underlying the anti-stress effect of Fu Zi remains unknown. In this study, researchers examined the effects of Fu Zi on the treatment of broilers exposed to Extreme Cold Stress (ECS). The levels of Nitric Oxide (NO) and creatine kinase in plasma were measured and Hsp70 mRNA expression in different tissues was analyzed. Broilers subjected to ECS exhibited increased NO content before 3 h and increased Hsp70 expression under a time and tissue-dependent manner. Biochemically, Fu Zi reversed ECS-induced increases in NO and Hsp70 mRNA and the results suggest that Fu Zi supplemented broilers kept an elevated plasma NO content through anti-oxidative activity during ECS. ER -