TY - JOUR
T1 - Antifungal Susceptibility of Dermatophytes Isolated from Domestic Calves in Thamar, Yemen
AU - Golah, H.A.M. AU - Khalel, A.S. AU - Khaled, J.M.A. AU - Shine, K.
JO - Journal of Animal and Veterinary Advances
VL - 11
IS - 24
SP - 4544
EP - 4548
PY - 2012
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2012.4544.4548
UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.4544.4548
KW - Dermatophytes
KW -calves
KW -NCCLS
KW -in vitro
KW -antifungi
AB - This research aimed to isolate and identify some dermatophytes
which causing ringworm disease in calves in Thamar government, Yemen Republic
and evaluate antifungal susceptibility of isolates against some common chemical
compounds (CuSO4+CaO, Formaldehyde and Hydrogen Peroxide and Amphotericin
B was used as standard antifungal agent). A total of 139 samples were collected
from head, chest and limbs of calves which infected by ringworm disease. Dermatophytes
Test Medium (DTM) was used to differ between dermatophyte and non dermatophyte
fungi. Only 11 isolates were considered dermatophytes. Macro and microcharacteristics
were studied to identify the dermatophyte isolates. All isolates were identified
as Trichophytonverrucosum. The identification of the isolates were confirmed
by Assiut University Mycological Center (AUMC), Egypt and were given AUMC NO.
2407. In vitro antifungal susceptibility test was performed according
to Committee for Clinical Laboratory Standards for filamentous fungi (NCCLS
M38-A) guidelines. The study concluded that T. verrucosum could be major
causative agent of ringworm disease in calves in Thamar, Yemen. Of all the farms,
the farms of government sector had the highest ringworm disease prevalence rate.
In vitro activity of Formaldehyde solution (10%) against T. verrucosum
isolated from calves was more than mixture of cupric sulphate with calcium oxide
and hydrogen peroxide. It could be used as antifungal drugs to treat ringworm
disease in calves in Yemen.
ER -