TY  - JOUR
T1  - Study of Relationship between Testosterone and Dermatophytosis due to <I>Trichophyton verrucosum</I>
AU - Gharachorloo, Aliasghar AU - Ajoudanifar, Hatef 
JO  - Journal of Animal and Veterinary Advances
VL  - 11
IS  - 21
SP  - 4013
EP  - 4016
PY  - 2012
DA  - 2001/08/19
SN  - 1680-5593
DO  - javaa.2012.4013.4016
UR  - https://makhillpublications.co/view-article.php?doi=javaa.2012.4013.4016
KW  - Androgenic hormones
KW  -testosterone
KW  -dermatophytosis
KW  -Trichophyton verrucosum
KW  -Iran
AB  - The inhibitory effect exerted by steroid hormones on the <I>in vitro</I> growth characteristics of dermatophytes is poorly understood. As a hypothesis this inhibition could result from fungal adaptation to the human host. Therefore, in this study the susceptibility of <I>T. verrucosum</I> to androgenic hormones was done. As a result, testosterone proved to reduce fungal growth whereas hydrocortisone had no such effect. In general, <I>T. verrucosum</I> was shown to be more susceptible to steroid hormones. However, since fungal response to hormones consisted of growth inhibition and occurred only at steroid concentrations much higher than present in human, it cannot be assumed to contribute to this adaptation.
ER  -