TY - JOUR T1 - Hypotheses: A New Way Against Cancer Metastasis, Chitooligosaccharides as Mucosal Adjuvant for Therapeutic Vaccination Targeting Heparanase AU - Xu, Zirong AU - Quan, Haizhi JO - Journal of Animal and Veterinary Advances VL - 11 IS - 15 SP - 2788 EP - 2791 PY - 2012 DA - 2001/08/19 SN - 1680-5593 DO - javaa.2012.2788.2791 UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.2788.2791 KW - Heparanase KW -chitooligosaccharide KW -tumor metastasis KW -adjuvant KW -cancer vaccine AB - Heparanase is a tumor metastasis associated antigen so cancer vaccine targeting heparanase is an effective way to treat tumor metastasis. However, cancer vaccine needs adjuvant because of low immunostimulatory. Chitooligosaccharides (COS) has been proved to be an successful cancer vaccine adjuvant due to its propertied. COS will be a well adjuvant for cancer vaccine targeting heparanase. ER -