TY - JOUR
T1 - Effect of Iron Supplement on the Activity of Catalase, SDH and Their MRNA
Expression in Rex Rabbit
AU - Zhang, Zhao-Qin AU - Zhao, Xiang-Ru AU - Lian, Jun-Feng AU - Guan, Li-Hui AU - Zhang, Hai-Wang
JO - Journal of Animal and Veterinary Advances
VL - 11
IS - 13
SP - 2347
EP - 2351
PY - 2012
DA - 2001/08/19
SN - 1680-5593
DO - javaa.2012.2347.2351
UR - https://makhillpublications.co/view-article.php?doi=javaa.2012.2347.2351
KW - Iron
KW -enzymes
KW -rabbit
KW -SDH mRNA
KW -CAT mRNA
KW -China
AB - The effect of iron (Fe) supplement on the activity of Catalase (CAT) and Sorbitol Dehydrogenase (SDH) in blood and their mRNA expressions in liver cells of rex rabbits were evaluated. The rabbits were fed with basal diets supplemented with 0, 30, 60, 90, 120, 150 and 200 mg kg-1 (FeSO4H2O), respectively for 60 days. The added Fe significantly increased the activity of CAT and SDH in blood compared to controls (0 mg kg-1) but the amount added had little effect. Adding Fe at 30, 60, 90, 120, 150 and 200 mg kg-1 upregulated CAT gene expression by 45, 58, 67, 64, 61 and 63%, respectively. The corresponding gene upregulation for SDH were 41, 59, 71, 69, 67 and 68%. Fe supplement also increased the average daily weight gain and fresh fur areas. All the measurements reached a plateau around 90-120 mg kg-1 added Fe. The information provides a valuable reference to diet formulation optimization specifically for Rex rabbits.
ER -